Recent Advances for the Desaturation of Amides

ABSTRACT Enamides are important intermediates in organic synthesis, and the desaturation of amides represents an efficient and versatile approach for the synthesis of enamides. Recently, increasing efforts have been made to develop more efficient and sustainable methods for the desaturation of amide under different conditions. In this review, we summarized the most recent advances in the desaturation of amide, including transition‐metal‐catalyzed oxidative desaturation, transition‐metal‐free oxidative desaturation, photoinduced redox desaturation, and electrochemical anodic oxidative desaturation. The substrate scope and mechanistic details were also discussed.