Key result
Aggressive management of modifiable cardiovascular risk factors, including hypertension, obesity, sleep apnea, and physical inactivity, beneficially affects atrial fibrillation pathogenesis and improves treatment outcomes.
Why the study?
Emerging data suggest that optimizing modifiable cardiovascular risk factors could beneficially affect AF pathogenesis and outcomes, but pragmatic interventions require examination.
Does modification of extracardiac cardiovascular risk factors improve outcomes in patients with atrial fibrillation?
Does modification of extracardiac cardiovascular risk factors improve outcomes in patients with atrial fibrillation?
Aggressive modification of cardiovascular risk factors, including weight loss, exercise, and control of hypertension and sleep apnea, is a critical pillar in the comprehensive management of atrial fibrillation.
Risk factor optimization may beneficially influence AF; leaves open whether targeted interventions improve outcomes in practice.
Atrial fibrillation (AF) is a chronic progressive disease. The contemporary management of AF is centered on promoting a reduction in the rates of morbidity and mortality associated with the condition. While stroke prevention and rate/rhythm management remain the cornerstones of AF care, recently, there has been increasing interest arising in addressing modifiable cardiovascular risk factors. Emerging data suggest that the optimization of these could beneficially affect AF pathogenesis and associated outcomes. The purpose of this review was to examine common modifiable risk factors with a look to pragmatic intervention.
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Andrade et al. (2019) conducted a review in Atrial fibrillation. Modifiable cardiovascular risk factor management vs. Usual care or no risk factor modification was evaluated. Aggressive management of modifiable cardiovascular risk factors, including hypertension, obesity, sleep apnea, and physical inactivity, beneficially affects atrial fibrillation pathogenesis and improves treatment outcomes.
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