Towards Understanding Deterioration in Systemic Right Ventricular Function in the Setting of Tricuspid Regurgitation: Is There a Point of No Return?

The field of adult congenital heart disease (ACHD) has continued to expand over the last few decades, with adults now outnumbering children living with congenital heart disease (CHD).1,2 Although many of these patients have undergone surgical intervention which result in a relatively “normal” circulation, a large percentage are left with persistent anatomic and physiologic abnormalities when compared with the general population. Prime examples are those with a systemic right ventricle (sRV), such as patients with d-transposition of the great arteries (D-TGA) who have undergone an atrial switch operation or those with congenitally corrected transposition (ccTGA).