Key result
Right ventricular myocardial work indices, including RV global work index, showed significant correlations with RV global longitudinal strain and pulmonary systolic artery pressure (p < 0.0001).
Why the study?
Correlations among right ventricular myocardial work indices and RV systolic and diastolic functions had not yet been studied.
Do noninvasive right ventricular myocardial work indices correlate with parameters of systolic and diastolic functions in healthy volunteers?
Observational (n=106)
Do noninvasive right ventricular myocardial work indices correlate with parameters of systolic and diastolic functions in healthy volunteers?
p-value: p=<.0001
Noninvasive right ventricular myocardial work indices show good correlations with established parameters of RV myocardial systolic function in healthy individuals.
Provides normative RV myocardial work correlations in healthy volunteers; leaves open diagnostic utility in disease pending prospective studies.
BACKGROUND: Right ventricular (RV) myocardial work (RVMW) is the latest method used to assess RV function. To date, correlations among RVMW indices and RV systolic and diastolic functions have not been studied. METHODS: A total of 106 healthy volunteers (median age, 34 years; 46% male) were prospectively enrolled. RVMW indices were measured using the RV pressure-strain loop using specific software. The correlations among RVMW indices and other RV functions were analyzed. RESULTS: During the multivariate analysis, the RV global work index (RVGWI) was significantly correlated with RV global longitudinal strain (RV GLS) (p < .0001), pulmonary systolic artery pressure (PASP) (p < .0001), and tricuspid annular (TA) plane systolic excursion (TAPSE) (p = .036). RV global constructive work (RVGCW) was correlated with RV GLS (p < .0001) and PASP (p < .0001). RV global wasted work (RVGWW) was correlated with RV GLS (p = .008) and TA isovolumetric acceleration (TA IVA) (p = .008). RV global work efficiency (RVGWE) was correlated with RV GLS (p < .0001) and tissue Doppler (TD) RV myocardial performance index (TD RMPI) (p = .043). CONCLUSION: RVMW indices showed good correlations with RV myocardial systolic function.
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Wu et al. (2022) conducted an observational in Healthy volunteers (n=106). Right ventricular myocardial work (RVMW) indices was evaluated on Correlations among RVMW indices and RV systolic and diastolic functions (p=<.0001). Right ventricular myocardial work indices, including RV global work index, showed significant correlations with RV global longitudinal strain and pulmonary systolic artery pressure (p < 0.0001).
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