Key result
Dual chamber pacemaker implantation successfully reduced the peak instantaneous left ventricular outflow tract gradient from 194 mm Hg to 37 mm Hg in a patient with hypertrophic obstructive cardiomyopathy.
Why the study?
Does dual chamber pacemaker implantation improve LVOT gradient and symptoms in a patient with HOCM and absent major septal perforator branch?
Case Report (n=1)
No
Does dual chamber pacemaker implantation improve LVOT gradient and symptoms in a patient with HOCM and absent major septal perforator branch?
Absolute Event Rate: 37% vs 194%
Dual chamber pacing remains a viable treatment option for relieving LVOT obstruction in HOCM patients who are unsuitable for surgical myectomy or alcohol septal ablation.
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May support pacing consideration in HOCM patients ineligible for septal reduction; leaves open need for controlled trials.
Albano et al. (2017) conducted a case report in Hypertrophic obstructive cardiomyopathy (n=1). Dual chamber pacemaker implantation vs. Baseline was evaluated on Peak instantaneous gradient across the basal LV segment (mm Hg). Dual chamber pacemaker implantation successfully reduced the peak instantaneous left ventricular outflow tract gradient from 194 mm Hg to 37 mm Hg in a patient with hypertrophic obstructive cardiomyopathy.
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