Key result
Neonates of pre-eclamptic mothers had significantly higher serum troponin T concentrations (0.70 vs 0.10 ng/ml) and altered mitral flow velocities compared to healthy full-term controls.
Why the study?
Does maternal mild pre-eclampsia increase serum Troponin T concentrations and alter echocardiographic parameters in neonates compared to healthy controls?
Population
32 neonates, including 15 neonates of mild pre-eclamptic mothers and 17 healthy full-term neonates as a…
Comparison
Exposure to maternal mild pre-eclampsia. vs Healthy full-term neonates.
Design
Case-control
Authors
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May detect subclinical myocardial injury in neonates of pre-eclamptic mothers; hypothesis-generating and should not yet change practice.
Case-Control (n=32)
Does maternal mild pre-eclampsia increase serum Troponin T concentrations and alter echocardiographic parameters in neonates compared to healthy controls?
Absolute Event Rate: 0.7% vs 0.1%
Neonates born to mothers with mild pre-eclampsia exhibit elevated Troponin T levels and altered diastolic echocardiographic parameters, suggesting the presence of mild myocardial damage.
Narın et al. (1998) conducted a case-control in Neonates of pre-eclamptic mothers (n=32). Maternal pre-eclampsia vs. Healthy full-term neonates was evaluated on Serum troponin T (TnT) concentration. Neonates of pre-eclamptic mothers had significantly higher serum troponin T concentrations (0.70 vs 0.10 ng/ml) and altered mitral flow velocities compared to healthy full-term controls.
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