Key result
Metabolic syndrome components significantly increased the risk of venous thromboembolism recurrence in patients with deep vein thrombosis, with hyperlipidemia conferring the highest risk (OR 1.8).
Why the study?
Data linking venous thromboembolism (VTE) recurrence with metabolic syndrome remain limited, despite its known association with a hypofibrinolytic state.
Does metabolic syndrome increase the risk of VTE recurrence in patients with deep vein thrombosis?
Population
151 054 patients with DVT
Comparison
Patients with metabolic syndrome components vs without
Design
Retrospective database analysis
Authors
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MetS may flag higher VTE recurrence risk; leaves open whether targeting components alters outcomes.
Cohort (n=151,054)
Yes
Does metabolic syndrome increase the risk of VTE recurrence in patients with deep vein thrombosis?
Odds Ratio: 1.8
Metabolic syndrome and its individual components, particularly hyperlipidemia, are significantly associated with an increased risk of VTE recurrence in patients with DVT.
Stewart et al. (2020) conducted a cohort in Deep vein thrombosis (n=151,054). Metabolic syndrome vs. Absence of metabolic syndrome components was evaluated on Venous thromboembolism recurrence (OR 1.8). Metabolic syndrome components significantly increased the risk of venous thromboembolism recurrence in patients with deep vein thrombosis, with hyperlipidemia conferring the highest risk (OR 1.8).
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