Key result
Prenatally detected atrioventricular septal defect was associated with a poor prognosis, yielding only 4 survivors out of 29 cases (13.8%), often with chromosomal or structural anomalies.
Population
29 fetuses with atrioventricular septal defect detected prenatally out of a series of more than 3500…
Design
Case_series
Follow-up
until term/postnatal survival
Authors
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Warrants detailed genetic counseling in fetal AVSD; leaves open whether interventions can alter outcomes in this population.
Observational (n=29)
Prenatal detection of atrioventricular septal defect is associated with a high rate of chromosomal anomalies, isomerism, and poor overall survival.
Machado et al. (1988) conducted an observational in Atrioventricular septal defect (n=29). Atrioventricular septal defect was evaluated on Survival. Prenatally detected atrioventricular septal defect was associated with a poor prognosis, yielding only 4 survivors out of 29 cases (13.8%), often with chromosomal or structural anomalies.
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