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June 4, 2021AntibioticsOpen Access

Advances in Bacteriophage Therapy against Relevant MultiDrug-Resistant Pathogens

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Authors

ABAntonio Broncano-LavadoGSGuillermo Santamaría-CorralJEJaime Esteban

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Overview

Review summarizes phage therapy's effectiveness against multiDrug-resistant infections, indicating its potential benefit.

Key Points

  • This review aims to explore bacteriophage therapy as a novel treatment option for multidrug-resistant bacterial infections.
  • Analyzed recent clinical trials, animal models, and case reports of phage therapy applications.
  • Examined the effectiveness of combining phage therapy with antibiotics against resistant strains.
  • Discussed limitations and challenges in implementing phage therapy in clinical settings.
  • Phage therapy shows improved effectiveness against carbapenem-resistant A. baumannii and P. aeruginosa strains when used with antibiotics.
  • Clinical cases indicate successful infections management after conventional therapies failed due to multidrug resistance.
  • The review highlights ongoing challenges in phage therapy, including regulatory hurdles and variability in therapeutic efficacy.

Cite This Study

Broncano-Lavado et al. (2021) studied this question.

synapsesocial.com/papers/6a64fb66ca348e561ba8a048https://doi.org/10.3390/antibiotics10060672
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