Surgery before 12 hours for hip fracture improved 30-day survival compared with surgery after 12 hours (p=0.013), while further delays did not significantly affect mortality.
Observational (n=6,638)
No
Does surgery before 12 hours reduce 30-day mortality in patients aged > 60 years with a hip fracture?
In patients over 60 years old with a hip fracture, surgery within 12 hours of admission significantly improves 30-day survival compared to surgery delayed beyond 12 hours.
p-value: p=0.013
There has been extensive discussion about the effect of delay to surgery on mortality in patients sustaining a fracture of the hip. Despite the low level of evidence provided by many studies, a consensus has been accepted that delay of > 48 hours is detrimental to survival. The aim of this prospective observational study was to determine if early surgery confers a survival benefit at 30 days. Between 1989 and 2013, data were prospectively collected on patients sustaining a fracture of the hip at Peterborough City Hospital. They were divided into groups according to the time interval between admission and surgery. These thresholds ranged from 60 years were included. Worsening American Society of Anaesthesiologists grade (p < 0.001), increased age (p < 0.001) and extracapsular fracture (p < 0.019) increased the risk of 30-day mortality. Increasing mobility score (p = 0.014), mini mental test score (p < 0.001) and female gender (p = 0.014) improved survival. After adjusting for these confounders, surgery before 12 hours improved survival compared with surgery after 12 hours (p = 0.013). Beyond this the increasing delay to surgery did not significantly affect the 30-day mortality.
Bretherton et al. (Thu,) conducted a observational in Fracture of the hip (n=6,638). Surgery before 12 hours vs. Surgery after 12 hours was evaluated on 30-day mortality (p=0.013). Surgery before 12 hours for hip fracture improved 30-day survival compared with surgery after 12 hours (p=0.013), while further delays did not significantly affect mortality.
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