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January 1, 1997Journal of Biological ChemistryOpen Access

Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation

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Authors

LLLongbin LiuNational University of Defense TechnologyJFJohn FreedmanSt. Michael's HospitalAHAdriana HornsteinSt. Michael's Hospital

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Cite This Study

Liu et al. (1997) studied this question.

synapsesocial.com/papers/6a650936dfe9f9fc9bef3fc4https://doi.org/10.1074/jbc.272.3.1997
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Also Consider

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  1. 1Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system1995 · 35 citations
  2. 2Issues in the Development of Thrombin Receptor Antagonists1995 · 29 citations
  3. 3Activation of platelets by alpha-thrombin is a receptor-mediated event. D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone-thrombin, but not N alpha-tosyl-L-lysine chloromethyl ketone-thrombin, binds to the high affinity thrombin receptor.1986 · 88 citations
  4. 4Efficient production of chicken egg yolk antibodies against a conserved mammalian protein1990 · 382 citations
  5. 5Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment1993 · 52 citations