A new therapeutic approach to treating atherosclerosis? The chiral, D2-symmetrical cyclophane 1 is a selective receptor for cholesterol in water and dissolves the insoluble solid steroid efficiently through inclusion complexation. The cavity of 1 with dimensions of 9 x 13 x 11 Å has the ideal shape and hydrophobic surface for encapsulating steroids.
No takes yet. Share an insight, caveat, or question.
Peterson et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: