Key result
Hawthorn shows potential cardiovascular benefits, particularly in congestive heart failure.
Hawthorn (Crataegus) may play a role in the prevention and treatment of cardiovascular diseases such as hypertension, hyperlipidemia, and in particular, congestive heart failure. Evidence is accumulating that hawthorn may induce anti-ischemia/reperfusion-injury, anti-arrhythmic, hypolipidemic and hypotensive effects. These beneficial effects may in part be due to the presence of antioxidant flavonoid components. While a number of studies have been performed to evaluate the clinical efficacy of hawthorn, an international, multicenter, prospective clinical study including a large number of New York Heart Association (NYHA) class II/III heart failure patients is ongoing to test hawthorn's long-term therapeutic effects. Further clinical trials as well as pharmacokinetic and mechanistic studies are needed to explore and confirm its effectiveness, safety and pharmacological mechanism.
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Chang et al. (2005) conducted a review in Cardiovascular disease (hypertension, hyperlipidemia, congestive heart failure). Hawthorn (Crataegus) was evaluated. Hawthorn may offer beneficial therapeutic effects for cardiovascular diseases such as congestive heart failure, though quantitative clinical efficacy results are not reported.
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