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Shows T cell vaccination reduces autoimmune response in experimental models, suggesting new therapeutic strategies.
T cell vaccination against experimental autoimmune disease is herein shown to be mediated in part by anti-ergotypic T cells, T cells that recognize and respond to the state of activation of other T cells. The anti-ergotypic response thus combines with the previously shown anti-idiotypic T cell response to regulate autoimmunity.
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Lohse et al. (1989) studied this question.
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