Key result
In stable COPD patients attending pulmonary rehabilitation, 77% of completers showed clinically significant benefit, though depression increased drop-out risk and MRC grade 5 limited improvement.
Why the study?
Do baseline clinical variables predict response or drop-out in stable COPD patients undergoing pulmonary rehabilitation?
Cohort (n=74)
Do baseline clinical variables predict response or drop-out in stable COPD patients undergoing pulmonary rehabilitation?
Baseline clinical variables poorly predict response to pulmonary rehabilitation in COPD, though severe dyspnea limits improvement and depression increases the risk of drop-out.
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Supports depression screening to reduce drop-out in COPD rehabilitation; leaves open reliable response predictors.
Garrod et al. (2006) conducted a cohort in chronic obstructive pulmonary disease (COPD) (n=74). Baseline characteristics (MRC dyspnoea score, depression) vs. Patients with less severe MRC dyspnoea score grades / nondepressed patients was evaluated on Response to rehabilitation (change in SGRQ of 4 points or 6MWD of 54 m). In stable COPD patients attending pulmonary rehabilitation, 77% of completers showed clinically significant benefit, though depression increased drop-out risk and MRC grade 5 limited improvement.
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