Key result
Septic shock was associated with elevated cardiac troponin I levels in 80% of patients, significantly higher than in critically ill controls without septic shock (p=0.01).
Why the study?
Are cardiac troponin I levels elevated in patients with septic shock compared to critically ill controls without septic shock?
Observational (n=21)
No
Are cardiac troponin I levels elevated in patients with septic shock compared to critically ill controls without septic shock?
Elevated cardiac troponin I is common in septic shock and correlates with cardiac dysfunction, vasoactive drug requirements, and mortality.
Answers are grounded in this paper and cite their sources.
Troponin elevation signals myocardial injury linked to worse hemodynamics and mortality in septic shock; hypothesis-generating for targeted cardiac interventions.
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Turner et al. (1999) conducted an observational in Septic shock (n=21). Septic shock vs. Mechanically ventilated patients without septic shock was evaluated on Elevated serum cardiac troponin I (cTN I) concentrations (p=.01). Septic shock was associated with elevated cardiac troponin I levels in 80% of patients, significantly higher than in critically ill controls without septic shock (p=0.01).
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