Key result
Length of stay and polypharmacy independently predicted weight gain, while the triglyceride/high-density lipoprotein ratio was inversely associated with weight gain (P=0.063).
Why the study?
What factors predict weight gain in psychiatric inpatients receiving short-term treatment?
Observational (n=221)
What factors predict weight gain in psychiatric inpatients receiving short-term treatment?
Length of hospitalization and polypharmacy with second-generation antipsychotics and mood stabilizers strongly predict weight gain in psychiatric inpatients.
Weight monitoring may be considered for longer-stay inpatients on combined SGA-mood stabilizer therapy; leaves open causal effects and intervention needs.
INTRODUCTION: The aim of this study was to investigate the factors associated with weight gain by psychiatric inpatients in short-term treatment. METHODS: A total of 378 medical records were reviewed, and sociodemographic, clinical, and baseline biochemical data from 221 psychiatric inpatients were analyzed. RESULTS: Evaluation of baseline characteristics indicated that the following were significant predictors of weight gain: Axis I diagnosis, treatment with second-generation antipsychotics and mood stabilizers, length of stay, admission body weight, low-density lipoprotein value, triglyceride level, and triglyceride/high-density lipoprotein ratio. Multiple linear regression analysis showed that the independent predictors of weight gain were length of stay and taking both a second-generation antipsychotic and a mood stabilizer. The triglyceride/high-density lipoprotein ratio was an influencing factor inversely associated with weight gain (P = 0.063). DISCUSSION: Length of hospitalization and polypharmacy strongly predicted weight gain among psychiatric inpatients receiving short-term treatment.
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Liu et al. (2012) conducted an observational in psychiatric inpatients (n=221). Length of stay and polypharmacy (second-generation antipsychotic and mood stabilizer) was evaluated on weight gain. Length of stay and polypharmacy independently predicted weight gain, while the triglyceride/high-density lipoprotein ratio was inversely associated with weight gain (P=0.063).
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