Key result
Prolonged QTc was an independent predictor of all-cause mortality in end-stage renal disease patients evaluated for transplantation (HR 1.008; 95% CI 1.001-1.014; P=0.016).
Why the study?
Does prolonged QTc predict all-cause mortality in ESRD patients evaluated for renal transplantation?
Cohort (n=280)
No
Does prolonged QTc predict all-cause mortality in ESRD patients evaluated for renal transplantation?
Hazard Ratio: 1.008 (95% CI 1.001–1.014)
Absolute Event Rate: 47% vs 36%
p-value: p=0.016
QTc prolongation is an independent predictor of mortality in ESRD patients evaluated for renal transplantation, providing additive prognostic information to LVEF and CAD severity.
Authors
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Prolonged QTc may signal higher mortality risk in ESRD transplant candidates; leaves open incremental value beyond standard stratification in prospective studies.
Hage et al. (2010) conducted a cohort in End-stage renal disease (ESRD) (n=280). Prolonged QTc vs. Normal QTc was evaluated on All-cause mortality (HR 1.008, 95% CI 1.001-1.014, p=0.016). Prolonged QTc was an independent predictor of all-cause mortality in end-stage renal disease patients evaluated for transplantation (HR 1.008; 95% CI 1.001-1.014; P=0.016).
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