Key result
Cellular calcium alternans is proposed as an important mechanism linking mechanical dysfunction to cardiac arrhythmogenesis and sudden cardiac death.
Design
Review
Authors
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May link calcium alternans to SCD risk in HF; hypothesis-generating and requires prospective validation before clinical translation.
Cellular calcium alternans is proposed as a key mechanistic link between heart failure-induced mechanical dysfunction and the risk of sudden cardiac death.
Wilson et al. (2006) conducted a review in Ventricular dysfunction and sudden cardiac death. Cellular calcium alternans was evaluated. Cellular calcium alternans is proposed as an important mechanism linking mechanical dysfunction to cardiac arrhythmogenesis and sudden cardiac death.
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