What question did this study set out to answer?

To examine whether physical trauma and vigorous physical activity are associated with the risk of developing amyotrophic lateral sclerosis (ALS).

July 1, 1996Acta Neurologica Scandinavica

Physical activity, trauma, and ALS: a case-control study

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Authors

DSDaniel StricklandMedical Research Associates SSStephen A. SmithAfrican Wildlife Foundation GDG. DolliffUniversity of Minnesota

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Implication

Case-control study reveals severe injury and frequent vigorous physical activity are associated with amyotrophic lateral sclerosis, suggesting potential environmental or neuromuscular triggers.

Key Points

To examine whether physical trauma and vigorous physical activity are associated with the risk of developing amyotrophic lateral sclerosis (ALS).
Conducted a pilot case-control study evaluating patients with ALS from a university muscle disease clinic.
Paired each case with two matched controls: one clinic-based control diagnosed with a different disease and one population-based community control.
Severe injury to the head, neck, and back was strongly associated with ALS compared to matched controls (OR = 5.3).
Significant associations were observed for frequent sweating during work (OR = 1.6), frequent sweating during leisure activity (OR = 1.6), and earning a school athletic letter (OR = 3.1; p < 0.05).

Cite This Study

Strickland et al. (1996) studied this question.

synapsesocial.com/papers/6a654b482130db5e95b2e724 https://doi.org/10.1111/j.1600-0404.1996.tb00038.x

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Implication

Case-control study reveals severe injury and frequent vigorous physical activity are associated with amyotrophic lateral sclerosis, suggesting potential environmental or neuromuscular triggers.

Physical activity, trauma, and ALS: a case-control study

Discussion

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Implication

Key Points

Cite This Study

Physical activity, trauma, and ALS: a case-control study

Discussion

Member takes

Implication

Key Points

Cite This Study

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