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This research examines the correlation between ribosomal protein genes and Minute loci in Drosophila melanogaster.

October 10, 2007Genome biologyOpen Access

The ribosomal protein genes and Minute loci of Drosophila melanogaster

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Systematic analysis reveals the molecular basis of Minute loci and their relationship with ribosomal protein genes.

This research examines the correlation between ribosomal protein genes and Minute loci in Drosophila melanogaster.
Conducted a systematic analysis using bioinformatic and genetic approaches.
Identified 88 cytoplasmic ribosomal protein (CRP) genes and 75 mitochondrial ribosomal protein (MRP) genes.
Defined 65 discrete Minute loci through genetic criteria and assessed their correspondence to CRP genes.
Identified 64 out of 65 Minute loci correspond to cytoplasmic ribosomal protein genes.
Nine CRP genes were found to exist as duplicates, but only one is consistently expressed.
MRP genes and more than 20 CRP genes do not correspond to Minute loci.

Marygold et al. (2007) studied this question.

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