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Anionic and cationic resins-adsorbed fractions of 44 lichens, hot water extracts of 9 lichens, and 20 lichen metabolites and their degradation products were assayed for their antitumor activity by the use of ascitic or solid-type Ehrlich carcinoma. Among them, the adsorbed fraction of Ramalina almquistii VAIN., d-protolichesterinic acid (1) and nephrosterinic acid (2) were effective against the solid-type Ehrlich carcinoma.
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Hirayama et al. (1980) studied this question.
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