Why the study?
How does ventricular deformation differ between adults with repaired Tetralogy of Fallot and healthy controls?
Population
94 adults with repaired Tetralogy of Fallot and 85 healthy controls of similar age and sex.
Comparison
Myocardial deformation imaging to assess… vs Healthy controls
Design
Cross-sectional
Key result
Adults with repaired Tetralogy of Fallot had significantly lower right ventricular free wall strain compared to healthy controls (-18.1% vs. -26.5%, P<0.001).
Authors
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RV/LV deformation changes in repaired ToF with PR are hypothesis-generating; prospective studies needed before guiding intervention timing.
Cross-Sectional (n=179)
How does ventricular deformation differ between adults with repaired Tetralogy of Fallot and healthy controls?
Absolute Event Rate: -18.1% vs -26.5%
p-value: p=<0.001
Adults with repaired Tetralogy of Fallot exhibit decreased right and left ventricular longitudinal strain compared to healthy controls, indicating biventricular dysfunction.
Menting et al. (2015) conducted a cross-sectional in Repaired Tetralogy of Fallot (n=179). Repaired Tetralogy of Fallot vs. Healthy controls was evaluated on Right ventricular free wall strain (p=<0.001). Adults with repaired Tetralogy of Fallot had significantly lower right ventricular free wall strain compared to healthy controls (-18.1% vs. -26.5%, P<0.001).