Key result
Adults with repaired Tetralogy of Fallot had severely decreased peak oxygen uptake, which correlated with left ventricular end-diastolic volume (r=0.38, p=0.01) and LV mass (r=0.42, p=0.006).
Population
52 adult patients who underwent Tetralogy of Fallot repair at a young age, and 33 age- and sex-matched…
Design
Cohort
Authors
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Biventricular function and PR severity on CMR may relate to exercise tolerance after ToF repair; leaves open their utility for risk stratification or intervention timing.
Cohort (n=85)
In adults with repaired Tetralogy of Fallot, decreased exercise capacity correlates with impaired right ventricular function and left ventricular dysfunction, suggesting significant right-to-left ventricular interaction.
Dłużniewska et al. (2017) conducted a cohort in Repaired Tetralogy of Fallot (n=85). Repaired Tetralogy of Fallot vs. Age- and sex-matched healthy volunteers was evaluated on Exercise tolerance (VO2peak). Adults with repaired Tetralogy of Fallot had severely decreased peak oxygen uptake, which correlated with left ventricular end-diastolic volume (r=0.38, p=0.01) and LV mass (r=0.42, p=0.006).
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