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The binding of IgE to surface receptors on rat basophilic leukemia cells is a simple reversible reaction with high affinity (KA = 6 x 10^9 M^-1) and between 300,000 to over 1,000,000 binding sites per cell, which can be completely dissociated at pH 3.0 without damaging the receptors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1974The Journal of Experimental MedicineOpen Access

THE INTERACTION OF IgE WITH RAT BASOPHILIC LEUKEMIA CELLS

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AKAnthony KulczyckiWashington University in St. Louis HMHenry MetzgerNational Institutes of Health

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Kulczycki et al. (1974) studied this question.

synapsesocial.com/papers/6a659873f3bdf71dcbd69c7b https://doi.org/10.1084/jem.140.6.1676

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December 1, 1974The Journal of Experimental MedicineOpen Access

THE INTERACTION OF IgE WITH RAT BASOPHILIC LEUKEMIA CELLS

View Full Paper

Ask AI

Bookmark

Authors

AKAnthony KulczyckiWashington University in St. Louis HMHenry MetzgerNational Institutes of Health

Discussion

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Kulczycki et al. (1974) studied this question.

synapsesocial.com/papers/6a659873f3bdf71dcbd69c7b https://doi.org/10.1084/jem.140.6.1676

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