Key result
Long sleep duration of more than 8 hours per night was associated with an increased risk of total stroke compared to 6-8 hours of sleep (HR 1.29, 95% CI 1.01-1.64).
Why the study?
Does long sleep duration increase the risk of stroke in a community-based cohort?
Cohort (n=95,023)
Yes
Does long sleep duration increase the risk of stroke in a community-based cohort?
Hazard Ratio: 1.29 (95% CI 1.01–1.64)
Absolute Event Rate: 4.39% vs 3.23%
Long sleep duration (>8 hours) is associated with an increased risk of total stroke, particularly in the elderly, and hemorrhagic stroke in women.
Long sleep duration was associated with higher stroke risk; leaves open causality and generalizability.
The objective of this study was to examine the relationship between sleep duration and ischemic and hemorrhagic stroke in a community-based cohort. The current analysis included 95,023 Chinese participants who were free of stroke at the baseline survey (2006-2007). Cox proportional hazards models were used to calculate hazard ratios (HRs) and their confidence intervals (CIs) for stroke, according to sleep duration. After a mean follow-up period of 7.9 years, 3,135 participants developed stroke (2,504 ischemic stroke and 631 hemorrhagic stroke). The full adjusted hazard ratio (95% CI) of total stroke (with 6-8 hours of night sleep being considered for the reference group) for individuals reporting greater than 8 hours was 1.29 (1.01-1.64). More significant association between long sleep duration and total stroke was found in the elderly (HR, 1.47; 95% CI, 1.05-2.07). Compared with participants getting 6-8 hours of sleep, only women who reported sleeping more than 8 hours per night were associated with hemorrhagic stroke (HR, 3.58; 95% CI, 1.28-10.06). This study suggested that long sleep duration might be a potential predictor/ marker for total stroke, especially in the elderly. And long sleep duration increased the risk of hemorrhagic stroke only in women.
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Song et al. (2016) conducted a cohort in Ischemic and hemorrhagic stroke (n=95,023). Long sleep duration (> 8 hours per night) vs. 6-8 hours of sleep per night was evaluated on Total stroke (HR 1.29, 95% CI 1.01-1.64). Long sleep duration of more than 8 hours per night was associated with an increased risk of total stroke compared to 6-8 hours of sleep (HR 1.29, 95% CI 1.01-1.64).
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