Key result
Circulating inflammatory, lipid, endothelial, cell adhesion, matrix degrading, and metabolic biomarkers are associated with carotid artery disease diagnosis and prognosis.
Why the study?
A definition of high-risk carotid plaques in asymptomatic patients is needed, and lack of robust clinical evidence limits using circulating biomarkers as standard of care.
Do circulating biomarkers assist in the diagnosis and prognosis of carotid artery disease to identify high-risk patients?
Design
Review paper
Authors
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May inform future carotid risk models; leaves open clinical adoption pending prospective validation.
Do circulating biomarkers assist in the diagnosis and prognosis of carotid artery disease to identify high-risk patients?
Circulating biomarkers show potential for identifying high-risk carotid artery plaques, but require more robust clinical evidence before standard clinical use.
Kigka et al. (2021) conducted a review in Carotid artery disease. Circulating biomarkers was evaluated. Circulating inflammatory, lipid, endothelial, cell adhesion, matrix degrading, and metabolic biomarkers are associated with carotid artery disease diagnosis and prognosis.
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