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July 26, 2026BMC Infectious DiseasesOpen Access

Antimicrobial resistance patterns and difficult-to-treat resistance in uropathogens among diabetic and non-diabetic patients: a cross-sectional study

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Authors

APAnkita PriyadarshiniPKPriyal KalolaHPHemantkumar Patadia

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Overview

Cross-sectional study investigates resistance patterns in uropathogens for diabetic and non-diabetic UTI patients, highlighting treatment complexities.

Key Points

  • This study aims to compare antimicrobial resistance patterns, particularly Difficult-to-Treat Resistance (DTR), in diabetic versus non-diabetic patients with urinary tract infections (UTIs).
  • Conducted a prospective observational cross-sectional study from August 2021 to January 2024 at a tertiary care teaching hospital.
  • Screened 2408 patients with UTI symptoms for urine culture and sensitivity, identifying 954 positive cases.
  • Analyzed resistance patterns of isolated uropathogens in both diabetic and non-diabetic cohorts.
  • 39.61% of screened individuals tested positive for UTIs, with 27.4% positivity in diabetics and 48.7% in non-diabetics.
  • P. aeruginosa exhibited the highest DTR in both groups, with significant resistance noted to penicillin (71.86%) and tetracycline (81.25%) in diabetics.
  • Nitrofurantoin and fosfomycin maintained high effectiveness in both diabetic and non-diabetic patients.

Cite This Study

Priyadarshini et al. (2026) studied this question.

synapsesocial.com/papers/6a65a3a3d3aea3239cd76a05https://doi.org/10.1186/s12879-026-13969-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multi-drug resistance and multiple antibiotic resistance index of uropathogens in diabetic and non-diabetic patients with urinary tract infections2026
  2. 2Prevalence and Antibiotic Susceptibility of Urinary Tract Infections in Diabetic and Non Diabetic Individuals: A Prospective Study2024
  3. 3Antimicrobial resistance of uropathogens in diabetic patients2025
  4. 4P-793. Antimicrobial Resistance of Uropathogens in Diabetic Patients2026
  5. 5A comparative study on prevalence of uropathogens and their antibiogram in diabetics and non-diabetics attending a tertiary care hospital2024