What does this research mean for the field?

Analysis of Russian search engine queries reveals that public interest in GLP-1 receptor agonists is heavily driven by weight loss and commercial intent rather than registered diabetes indications, and this search volume strongly correlates with actual pharmacy sales. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The study aims to analyze search queries related to GLP-1RAs and their correlation with pharmaceutical demand in Russia from 2018 to 2026.

July 26, 2026PharmacoepidemiologyOpen Access

Digital Pharmacoepidemiology of Glucagon-like Peptide-1 Receptor Agonists in Russia: A Retrospective Search Query Analysis (2018–2026)

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Authors

SKStanislav KotlyarovRyazan State University АКАнна Анатольевна КотляроваRyazan State Medical University named after Academician I.P. Pavlov

Discussion

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Implication

Retrospective study analyzes search trends of GLP-1RAs in Russia, highlighting demand discrepancies and implications.

Key Points

The study aims to analyze search queries related to GLP-1RAs and their correlation with pharmaceutical demand in Russia from 2018 to 2026.
Retrospective analysis of Yandex.Wordstat data over 97 months (March 2018 - March 2026)
Time series analysis, Herfindahl-Hirschman Index calculation, and semantic analysis of 4562 unique formulations
Validation with DSM Group pharmacy sales data.
46.05 million queries analyzed; interest in semaglutide increased 215-fold with a structural break in January 2021.
HHI decreased from 0.311 (concentrated market) to 0.141 (competitive market).
Strong correlation between search interest and pharmacy sales for Tirzetta (r = 0.976, p < 0.001).

Cite This Study

Kotlyarov et al. (2026) studied this question.

synapsesocial.com/papers/6a65a49fd3aea3239cd77306 https://doi.org/10.3390/pharma5030025

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July 26, 2026PharmacoepidemiologyOpen Access

Digital Pharmacoepidemiology of Glucagon-like Peptide-1 Receptor Agonists in Russia: A Retrospective Search Query Analysis (2018–2026)

View Full Paper

Ask AI

Bookmark

Authors

SKStanislav KotlyarovRyazan State University АКАнна Анатольевна КотляроваRyazan State Medical University named after Academician I.P. Pavlov

Discussion

Member takes

Implication

Retrospective study analyzes search trends of GLP-1RAs in Russia, highlighting demand discrepancies and implications.

Key Points

The study aims to analyze search queries related to GLP-1RAs and their correlation with pharmaceutical demand in Russia from 2018 to 2026.
Retrospective analysis of Yandex.Wordstat data over 97 months (March 2018 - March 2026)
Time series analysis, Herfindahl-Hirschman Index calculation, and semantic analysis of 4562 unique formulations
Validation with DSM Group pharmacy sales data.
46.05 million queries analyzed; interest in semaglutide increased 215-fold with a structural break in January 2021.
HHI decreased from 0.311 (concentrated market) to 0.141 (competitive market).
Strong correlation between search interest and pharmacy sales for Tirzetta (r = 0.976, p < 0.001).

Cite This Study

Kotlyarov et al. (2026) studied this question.

synapsesocial.com/papers/6a65a49fd3aea3239cd77306 https://doi.org/10.3390/pharma5030025

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