What question did this study set out to answer?

To evaluate the prognostic utility of HALP compared to DECAF scores in predicting 30-day mortality in acute exacerbations of COPD.

July 26, 2026BMC Pulmonary MedicineOpen Access

Comparison of HALP and DECAF in predicting 30 day in hospital mortality in a retrospective cohort study of acute exacerbation of COPD

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Retrospective cohort study compares HALP and DECAF scores to predict 30-day mortality in AECOPD, highlighting DECAF's superior accuracy.

To evaluate the prognostic utility of HALP compared to DECAF scores in predicting 30-day mortality in acute exacerbations of COPD.
Retrospective, single centre observational cohort study conducted between June 2022 and June 2025.
Included 499 adults presenting with acute exacerbation of COPD in the emergency department.
Calculated HALP and DECAF scores at admission and assessed discrimination using ROC analysis.
HALP score AUC=0.724 with a cut-off of 16.84, sensitivity 57.1%, specificity 75.0%, NPV 92.4%.
DECAF score AUC=0.932 with a cut-off of ≥ 4, sensitivity 76.2%, specificity 95.6%, NPV 96.5%.
DECAF demonstrated significantly better discrimination than HALP (DeLong p < 0.001).

Gode et al. (2026) studied this question.

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