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July 26, 2026PeerJOpen Access

Not all migrants are the same: geographic origin and long-term outcomes after first-episode psychosis—a retrospective cohort study

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Authors

ATAlba TollSSSara SillesYMYolanda Manzano

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Overview

Retrospective cohort study investigates psychiatric outcomes in migrant populations after first-episode psychosis, suggesting tailored treatment approaches.

Key Points

  • This study aims to explore how geographic origin and migration timing affect psychiatric outcomes following first-episode psychosis in migrants.
  • Retrospective cohort study conducted over 5 years on 184 patients attending Early Intervention Service
  • Patients grouped by geographic origin (e.g., Spanish, Latin American, Maghrebi, Sub-Saharan) and migration recency
  • Logistic regression and survival analyses to evaluate treatment adherence, relapse, and service disengagement.
  • Maghrebi origin linked to lower treatment adherence (OR = 0.32, 95% CI [0.12–0.89], p = 0.030)
  • Higher hazard of service disengagement for Maghrebi patients (HR = 2.42, 95% CI [1.10–5.34], p = 0.028)
  • Recent migrants (≤5 years) have increased disengagement hazard (HR = 2.89, 95% CI [1.30–6.40], p = 0.009), and Sub-Saharan origin is associated with earlier LAI antipsychotic initiation (HR = 3.40, 95% CI [1.58–7.32], p = 0.002).

Cite This Study

Toll et al. (2026) studied this question.

synapsesocial.com/papers/6a65a6f2d3aea3239cd78071https://doi.org/10.7717/peerj.21391
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of migration on first-episode psychosis clinical presentation at baseline2024
  2. 2Ethnic differences in pathways to obtain care, maintain care and engage to Early Intervention Service in Spain2024
  3. 3The impact of socioeconomic factors on the incidence and characteristics of first-episode psychosis2025 · 1 citations
  4. 4Risk Factors for Psychosis in the Migrant Population in Morocco2025
  5. 5Age-at-migration, ethnicity and psychosis risk: Findings from the EU-GEI case-control study2024 · 4 citations