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July 26, 2026Stroke0 citations

Acute Kidney Injury Linked to Intensive Blood Pressure Management Post-Thrombectomy

Acute Kidney Injury After Intensive Blood Pressure Lowering Following Successful Endovascular Thrombectomy

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Authors

JJJae Wook JungHKHee Byung KohYKYoung Dae Kim

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Overview

Randomized trial explores acute kidney injury post-thrombectomy in stroke patients, suggesting risks of intensive blood pressure lowering.

Key Points

  • To examine the impact of intensive blood pressure management on acute kidney injury development after endovascular thrombectomy in stroke patients.
  • Secondary analysis of the OPTIMAL-BP trial including patients with acute ischemic stroke post-thrombectomy.
  • Patients randomized to intensive (<140 mm Hg) or conventional (140-180 mm Hg) blood pressure management for 24 hours.
  • Multivariable logistic regression analyses performed adjusting for relevant clinical factors.
  • AKI within 7 days was higher in the intensive group (20/147, 13.6%) compared to conventional (9/140, 6.4%), adjusted odds ratio 2.54 (95% CI, 1.10-6.35).
  • Significantly lower rates of functional independence in AKI patients (13.8% vs. 49.0%), adjusted odds ratio 0.19 (95% CI, 0.05-0.55).
  • Higher stroke-related mortality at 3 months in AKI group (37.9% vs. 3.1%), adjusted odds ratio 13.8 (95% CI, 4.14-49.64).
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Cite This Study

Jung et al. (2026) studied this question.

synapsesocial.com/papers/6a65a72fd3aea3239cd78233https://doi.org/10.1161/strokeaha.126.056127
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