Suboptimal Glycemic Management and Overtreatment in Older Adults With Diabetes and Frailty

Diabetes mellitus remains a major contributor to morbidity and mortality among older adults. Despite advances in pharmacologic therapies and technologies, the proportion of older adults achieving guideline-recommended glycemic targets has declined. At the same time, risks associated with overtreatment, including hypoglycemia and adverse clinical outcomes, are increasingly recognized, particularly in those with frailty. This narrative summarizes current evidence supporting deprescribing interventions aimed at reducing overtreatment in older adults with diabetes and frailty. The review applies these findings to clinical case studies, offering practical guidance for nurse practitioners on initiating deprescribing strategies to promote more stable glycemic control in this vulnerable population.