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July 26, 2026The American Surgeon

Traumatic Brain Injury Identifies a High-Risk Phenotype in Blunt Cerebrovascular Injury

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Authors

DDDagmawi DemessieESElge StevensLPLinzi Paul

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Overview

Randomized trial examines mortality risk in blunt cerebrovascular injury patients with traumatic brain injury, suggesting closer evaluation is needed.

Key Points

  • This research aims to evaluate the effect of traumatic brain injury on mortality risk in patients with blunt cerebrovascular injury.
  • Identified adult BCVI patients diagnosed via CT angiography from a multicenter database across 52 trauma centers.
  • TBI was defined as acute intracranial injury on initial head CT, with BCVI severity categorized using Biffl grades.
  • Analyzed a total of 1,674 patients after excluding those with missing data.
  • Patients with TBI experienced higher in-hospital mortality (24.1% vs 6.4%; P < 0.0001).
  • In a multivariable analysis, TBI was associated with increased mortality risk (OR 1.63, 95% CI: 1.08-2.46; P = 0.02).
  • Stroke frequency was also higher in TBI patients (7.5% vs 3.3%; P = 0.0001).

Cite This Study

Demessie et al. (2026) studied this question.

synapsesocial.com/papers/6a65a76fd3aea3239cd783bbhttps://doi.org/10.1177/00031348261471488
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identifying Low-Risk Trauma Patients for Blunt Cerebrovascular Injury: Evidence From the North Carolina Trauma Registry2026
  2. 2Multicenter Evaluation of Functional Outcomes After Blunt Cerebrovascular Injury in Severe Traumatic Brain Injury2026 · 1 citations
  3. 3434 Concurrent Vascular and Traumatic Brain Injury: Effect on Patient Outcomes2024
  4. 4Incidence and Mechanisms of BCVI in Moderate to Severe TBI (P1-18.007)2026
  5. 5Augmenting Denver criteria yields increased BCVI detection, with screening showing markedly increased risk for subsequent ischemic stroke2019 · 40 citations