What question did this study set out to answer?

This study aims to evaluate the internal dose exposures of firefighters to various chemicals during WUI fire responses.

Urinary biomarkers of PAHs, VOCs, OPEs, and metal(loid)s in firefighters responding in the wildland urban interface (WUI)

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Randomized trial assesses urinary chemical exposures in firefighters, indicating significant health risks during WUI responses.

This study aims to evaluate the internal dose exposures of firefighters to various chemicals during WUI fire responses.
Enrolled 250 firefighters from Southern California into the Fire Fighter Cancer Cohort Study.
Collected urine samples at enrollment and post-fire, with a focus on 125 post-fire samples from 89 participants.
Analyzed samples for PAH metabolites, VOCs, OPEs, and metal(loid)s, comparing concentrations to general population data.
All seven PAH and 11 VOC metabolite concentrations significantly increased post-fire.
Diphenyl phosphate, antimony, and cadmium also showed significant increases.
Post-fire concentrations exceeded biological exposure indices for certain chemicals, with structure defense firefighters showing greater increases.

Calkins et al. (2026) studied this question.

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