What question did this study set out to answer?

To explore how admission hyperglycemia affects mortality and costs in acute ischemic stroke patients.

July 9, 2002Neurology

Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke

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Randomized trial examines hyperglycemia's impact on mortality and costs in ischemic stroke patients, suggesting need for better management.

To explore how admission hyperglycemia affects mortality and costs in acute ischemic stroke patients.
Analyzed data from 656 patients hospitalized for ischemic stroke from July 1993 to June 1998.
Defined hyperglycemia as blood glucose > or = 130 mg/dL and calculated hazard ratios for mortality using Cox regression.
Reviewed patient charts for stroke severity, blood glucose levels, and diabetes diagnoses.
40% of patients had hyperglycemia at admission; these patients had an average blood glucose of 206 mg/dL during their stay.
Patients with hyperglycemia experienced longer hospital stays (7 vs 6 days, p = 0.015) and higher charges ($6,611 vs $5,262, p < 0.001).
Hyperglycemia increased the risk of death at 30 days (HR 1.87, p < or = 0.01), 1 year (HR 1.75, p < or = 0.01), and 6 years (HR 1.41, p < or = 0.01).

Williams et al. (2002) studied this question.

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Randomized trial examines hyperglycemia's impact on mortality and costs in ischemic stroke patients, suggesting need for better management.