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July 24, 2026Annals of Laboratory MedicineOpen Access

Development and Validation of AurisC2-ID, a Fourier-Transform Infrared Spectroscopy Classifier for Differentiation of Clade II and Non-Clade II Candida auris Isolates

Yong Jun Kwon Jung‐Ah Kim Hyunseul Choi Minhee Kang Yukyung Jeon Tae Yeul Kim Eun Jeong Won

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Key Points

The aim is to develop and validate a classifier that distinguishes between Clade II and Non-Clade II Candida auris isolates.
Utilized Fourier-transform infrared spectroscopy for classification.
Validated the classifier against various Candida auris isolates including Clade II.
Performed statistical analyses to assess performance metrics.
The classifier achieved high accuracy in differentiating Clade II from Non-Clade II isolates.
Sensitivity and specificity rates reached 90% with a p-value <0.001 for statistical significance.
Validation confirmed reliability across multiple testing conditions.

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Implication

Demonstrates an effective method for differentiating isolates of Candida auris, implying enhanced diagnostic accuracy.

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Cite This Study

Kwon et al. (2026) studied this question.

synapsesocial.com/papers/6a65a91fd3aea3239cd790d1 https://doi.org/10.3343/alm.2026.0156

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