Prospective evaluation assesses virological outcomes in adherence-challenged individuals receiving injectable HIV therapy, suggesting improvements in care delivery.
Key Points
This evaluation aims to assess the implementation and outcomes of a clinical pathway for delivering LA-CAB/RPV to individuals facing adherence challenges in HIV treatment.
Prospective service evaluation across two Irish HIV centres
Multidisciplinary pathway designed for individuals unable to adhere to oral therapy
Assessment of virological control, treatment discontinuation, and injection timeliness during the first 16 months.
Of 51 screened individuals, 12 initiated treatment with LA-CAB/RPV; follow-up data was available for analysis.
All participants who commenced treatment with virological suppression maintained suppression; three out of nine with detectable viraemia achieved suppression.
Retention in care remained favourable with most delayed injections occurring within accepted dosing windows.