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July 26, 2026BiomedicinesOpen Access

Mechanisms of Hypertension in Women: Interactions Between Vascular Ageing, Metabolic Dysfunction, and Hormonal Regulation

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Authors

SHShiva HooshmandiNFNicholas S. FreestoneFAFrancesca Arrigoni

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Overview

Narrative review uncovers factors influencing hypertension in women, suggesting new avenues for cardiovascular risk management.

Key Points

  • This review aims to summarize the mechanisms by which vascular ageing, hormonal changes, and metabolic dysfunction affect hypertension in women.
  • Conducted a narrative review using PubMed, Scopus, and Google Scholar.
  • Synthesized clinical, epidemiological, and mechanistic studies on hypertension in women.
  • Excluded studies without defined menopausal status or documented reproductive milestones.
  • Menopause and vascular ageing significantly impact endothelial function and vascular resistance.
  • Chronic inflammation and genetic factors contribute to higher cardiovascular risk in women.
  • Emerging therapies like GLP-1 receptor agonists may enhance cardiovascular risk management in women.

Cite This Study

Hooshmandi et al. (2026) studied this question.

synapsesocial.com/papers/6a65a962d3aea3239cd793bahttps://doi.org/10.3390/biomedicines14081667
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