Key result
Erythrocyte-derived microparticles were significantly increased in patients with acute coronary syndrome compared to controls and positively correlated with coronary artery disease severity.
Why the study?
The predictive value of erythrocyte-derived microparticles (ErMPs) in patients with acute coronary syndrome (ACS) remained to be explored.
Is the concentration of erythrocyte-derived microparticles (ErMPs) associated with acute coronary syndrome risk and coronary artery disease severity?
Population
305 subjects
Comparison
ACS group vs control group
Authors
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Elevated ErMPs may support ACS risk assessment; hypothesis-generating and should not yet change practice.
Observational (n=305)
Is the concentration of erythrocyte-derived microparticles (ErMPs) associated with acute coronary syndrome risk and coronary artery disease severity?
Erythrocyte-derived microparticles may serve as a novel biomarker for predicting acute coronary syndrome risk and assessing coronary artery disease severity.
Liao et al. (2021) conducted an observational in Acute coronary syndrome (n=305). Erythrocyte-derived microparticles (ErMPs) vs. Control group was evaluated on ErMPs concentration and correlation with ACS risk and Gensini score. Erythrocyte-derived microparticles were significantly increased in patients with acute coronary syndrome compared to controls and positively correlated with coronary artery disease severity.
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