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January 1, 2015JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCHOpen Access

Evaluation of Endothelial and Platelet Derived Microparticles in Patients with Acute Coronary Syndrome

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Population

63 patients with acute coronary syndrome

Design

Cohort

Authors

MGMelvin George

Discussion

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Overview

Negative EMP/PMP-GRACE correlations in ACS should not change risk stratification; hypothesis-generating for protective microparticle effects.

Structured PICO

P
Population
63 patients with acute coronary syndrome (28 with ST elevation myocardial infarction [STEMI], 35 with non ST elevation myocardial infarction [NSTEMI])
O
Outcome
Levels of endothelial and platelet microparticles (EMP & PMP) and their correlation with disease severity (GRACE in-hospital score)surrogate

Endothelial and platelet microparticles are elevated in ACS, particularly in NSTEMI, and negatively correlate with GRACE scores, suggesting a potential protective effect.

Cite This Study

Melvin George (2015) studied this question.

synapsesocial.com/papers/6a1feccfc705fa157d0da07chttps://doi.org/10.7860/jcdr/2015/14493.6920
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