Key result
Imipramine demonstrated antidepressant properties in normal, asymptomatic subjects with varying levels of nonclinical depression.
Why the study?
Does imipramine improve antidepressant and anti-anxiety effects in nonhospitalized, asymptomatic subjects with varying levels of nonclinical depression?
Does imipramine improve antidepressant and anti-anxiety effects in nonhospitalized, asymptomatic subjects with varying levels of nonclinical depression?
Imipramine demonstrates antidepressant properties even in nonhospitalized, asymptomatic subjects with nonclinical depression.
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May warrant caution against use in non-depressed individuals; leaves open clinical relevance in major depression.
DiMascio et al. (1968) studied Nonclinical depression. Imipramine was evaluated on Antidepressant and anti-anxiety effects. Imipramine demonstrated antidepressant properties in normal, asymptomatic subjects with varying levels of nonclinical depression.