Key result
In heart failure patients undergoing CRT, atrial fibrillation without AVJ ablation was associated with higher mortality (HR 5.22; 95% CI 1.60-17.01) and lower responsiveness compared to sinus rhythm.
Why the study?
Does atrioventricular junction ablation improve outcomes in heart failure patients with atrial fibrillation undergoing cardiac resynchronization therapy compared to those without ablation or in sinus rhythm?
Population
131 consecutive heart failure patients undergoing cardiac resynchronization therapy (CRT) implantation
Comparison
Atrioventricular junction ablation in patients… vs Patients in sinus rhythm undergoing CRT, and AF…
Design
Cohort
Follow-up
12 months
Authors
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May support AVJ ablation in AF patients receiving CRT; leaves open need for randomized confirmation.
Cohort (n=131)
Does atrioventricular junction ablation improve outcomes in heart failure patients with atrial fibrillation undergoing cardiac resynchronization therapy compared to those without ablation or in sinus rhythm?
Hazard Ratio: 5.22 (95% CI 1.6–17.01)
p-value: p=0.006
In heart failure patients with atrial fibrillation undergoing CRT, concurrent AVJ ablation yields survival and clinical improvements comparable to patients in sinus rhythm.
Ferreira et al. (2008) conducted a cohort in Heart failure (n=131). Atrial fibrillation without atrioventricular junction (AVJ) ablation vs. Sinus rhythm was evaluated on Mortality (HR 5.22, 95% CI 1.60-17.01, p=0.006). In heart failure patients undergoing CRT, atrial fibrillation without AVJ ablation was associated with higher mortality (HR 5.22; 95% CI 1.60-17.01) and lower responsiveness compared to sinus rhythm.
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