Key result
Both resistance and endurance exercise training significantly increased the heart weight-to-body weight ratio and the number of cardiac telocytes compared to sedentary controls.
Why the study?
Telocytes are interstitial cells present in cardiac stem cell niches, but their response to cardiac growth induced by resistance and endurance exercise training remained unknown.
Does resistance or endurance exercise training increase cardiac telocytes and promote physiological cardiac growth in adult male rats?
Does resistance or endurance exercise training increase cardiac telocytes and promote physiological cardiac growth in adult male rats?
Absolute Event Rate: 5.05% vs 3.17%
p-value: p=<0.001
Both resistance and endurance exercise training increase cardiac telocytes and promote physiological cardiac growth in rats, independent of exercise type.
Telocyte increases with exercise training are hypothesis-generating in rats; leaves open any role in human physiological cardiac growth.
Telocytes are interstitial cells found in different tissues, including cardiac stem cell niches. The purpose of this study was to investigate the response of the telocytes to the cardiac growth that occurs in response to resistance and endurance exercise trainings using rats distributed into control, endurance, and resistance training groups. Results revealed that the ratio of heart weight to body weight, cardiomycyte number, cardiomyocyte area, thickness of the left ventricular wall were significantly higher in the training groups compared to the control group. We observed increment in the cardiomyocytes surface area and thickness of the left ventricular wall in the resistance-training group than endurance-training group. We conclude that both resistance and endurance exercise trainings will lead to an increased number of cardiac telocytes, consequently, promote activity of the cardiac stem cells, and results in physiological cardiac growth, and this response does not seem to depend on the type of exercise.
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Choobineh et al. (2023) studied Healthy (Physiological cardiac growth) (n=24). Resistance and endurance exercise training vs. No training (sedentary control) was evaluated on Heart weight-to-body weight ratio (mg/g) (p=<0.001). Both resistance and endurance exercise training significantly increased the heart weight-to-body weight ratio and the number of cardiac telocytes compared to sedentary controls.
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