Demonstrates cognitive benefits of exercise via extracellular vesicles, suggesting new neuroprotective strategies.
Exercise-induced muscle-brain communication mediated by extracellular vesicles. Physical exercise stimulates skeletal muscle to release extracellular vesicles (EVs) into the circulation. These vesicles may reach the brain and transfer bioactive cargo such as miRNA, thereby supporting neuronal function and brain homeostasis and potentially protecting against the onset or progression of neurodegenerative diseases.
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Fuller et al. (2026) studied this question.
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