Case report examines treatment options for haemophagocytic lymphohistiocytosis in typhoid fever, suggesting further exploration is needed.
Unlike haemophagocytic lymphohistiocytosis (HLH) induced by tuberculosis or rickettsial disease, there is no consensus for the treatment of HLH secondary to typhoid fever ( Salmonella Typhi). After a short illustrative example, we searched among the previously described cases of HLH secondary to typhoid fever to determine: (i) Is the specific treatment of HLH mandatory; and (ii) which option to choose between corticosteroids and intravenous immunoglobulins in association with antibiotherapy?
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Baumard et al. (2026) studied this question.
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