Key result
ICE and 3D mapping guide successful anteroseptal pathway ablation without AV nodal injury.
Why the study?
Cardiac dextroposition alters typical thoracic relationships, rendering conventional fluoroscopic landmarks unreliable and complicating electrophysiological procedures.
Does radiofrequency catheter ablation using 3D mapping and intracardiac echocardiography eliminate pre-excitation in a patient with cardiac dextroposition and WPW syndrome?
Case Report (n=1)
No
Does radiofrequency catheter ablation using 3D mapping and intracardiac echocardiography eliminate pre-excitation in a patient with cardiac dextroposition and WPW syndrome?
Radiofrequency ablation of an anteroseptal accessory pathway can be safely and effectively performed in patients with cardiac dextroposition by utilizing 3D electroanatomical mapping and intracardiac echocardiography to overcome altered fluoroscopic landmarks.
May support safe anteroseptal ablation in dextroposition using 3D mapping and ICE; leaves open generalizability beyond single cases.
Background Cardiac dextroposition involves a rightward shift of a normally configured heart, setting it apart from mirror-image dextrocardia. This anatomical variant can alter typical thoracic relationships, rendering conventional fluoroscopic reference points unreliable and increasing the complexity of electrophysiological procedures. Case summary A 57-year-old man was admitted following an out-of-hospital ventricular fibrillation arrest attributed to pre-excited atrial fibrillation. Chest radiography identified rightward displacement of the heart’s silhouette. Further diagnostic imaging confirmed cardiac dextroposition without abnormalities in atrioventricular or great-vessel orientation, thus distinguishing it from mirror-image dextrocardia. Electrophysiological study revealed that mapping the anteroseptal accessory pathway was complicated by altered fluoroscopic landmarks. Successful radiofrequency ablation was achieved with the aid of three-dimensional electroanatomical mapping and intracardiac echocardiography, resulting in the elimination of pre-excitation without causing atrioventricular nodal injury. Discussion The integration of advanced imaging modalities facilitated accurate localization and ablation, despite the abnormal cardiac position. This case demonstrates that even in the setting of significant anatomical displacement, safe and effective ablation of anteroseptal pathways can be accomplished through the application of multimodal mapping techniques.
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Kim et al. (2026) conducted a case report in Cardiac dextroposition with Wolff-Parkinson-White syndrome and pre-excited atrial fibrillation (n=1). Radiofrequency catheter ablation with 3D electroanatomical mapping and intracardiac echocardiography was evaluated on Elimination of pre-excitation (delta wave). Radiofrequency catheter ablation using 3D electroanatomical mapping and intracardiac echocardiography successfully eliminated pre-excitation without causing atrioventricular nodal injury.
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