Answers are grounded in this paper and cite their sources.
The mitochondrial respiratory chain has the crucial function of supplying the cell with energy in the form of ATP. Mutations affecting this chain can arise in mitochondrial or nuclear DNA and cause diseases known as mitochondrial encephalomyopathies. Because the rules of inheritance of mitochondrial and nuclear DNA differ considerably, these brain–muscle syndromes often have unpredictable clinical and genetic features.
No takes yet. Share an insight, caveat, or question.
DiMauro et al. (2003) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: