PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
July 28, 2026JCEM Case ReportsOpen Access

Carcinoid syndrome revealed by chronic diarrhea and isolated severe tricuspid regurgitation

View Full Paper
Ask AI
Bookmark
Share

Authors

DKDarpan KothiaOVOtto ValdesTPTushar Patel

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates relationship between chronic diarrhea and tricuspid regurgitation in a woman, highlighting the need for carcinoid syndrome evaluation.

Key Points

  • To explore the presentation of carcinoid syndrome in a patient with chronic diarrhea and heart issues.
  • Clinical evaluation of symptoms and vital signs, including serum sodium assessment,
  • Imaging through computed tomography (CT) for tumor identification,
  • Biochemical analysis of serum chromogranin A and urinary 5-HIAA for carcinoid diagnosis.
  • The patient presented with a serum sodium concentration of 114 mmol/L (reference range 135-145) indicating severe hyponatremia.
  • Transthoracic echocardiography revealed severe tricuspid regurgitation consistent with carcinoid heart disease (CHD).
  • Treatment with isotonic saline, octreotide, and furosemide improved the patient's hyponatremia and associated symptoms.

Cite This Study

Kothia et al. (2026) studied this question.

synapsesocial.com/papers/6a6850fb2845b684d16f0273https://doi.org/10.1210/jcemcr/luag191
View Full Paper
Ask AI
Bookmark
Share