Retrospective cohort study evaluates risk factors for hypertensive disorders in early-onset fetal growth restriction, suggesting intensified surveillance for high-risk individuals.
OBJECTIVE: Early onset fetal growth restriction (FGR) shares pathophysiologic origins and may precede the development of Hypertensive Disorder of Pregnancy (HDP). The aim of this study was to evaluate risk factors associated with the development of HDP in individuals with early onset FGR. METHODS: < 0.05. RESULTS: = 0.02), were significantly associated with the subsequent development of HDP. CONCLUSION: Among pregnancies with suspected early-onset FGR, an elevated UAPI (>95th percentile) was the strongest predictor of developing HDP. Additional risk factors included earlier gestational age at FGR diagnosis and an AC below the 5th percentile. Women with these risk factors warrant intensified maternal surveillance. Future studies integrating these clinical predictors with circulating angiogenic biomarkers may further refine risk stratification.
No takes yet. Share an insight, caveat, or question.
Sabag et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: